{"id":2055,"date":"2025-06-23T10:34:21","date_gmt":"2025-06-23T03:34:21","guid":{"rendered":"https:\/\/biomedmart.com.vn\/?p=2055"},"modified":"2025-06-23T10:39:56","modified_gmt":"2025-06-23T03:39:56","slug":"prp-va-ho-tro-sinh-san-huong-di-moi-cho-phu-nu-dap-ung-kem-voi-kich-thich-buong-trung-por","status":"publish","type":"post","link":"https:\/\/biomedmart.com.vn\/etc\/2025\/06\/23\/prp-va-ho-tro-sinh-san-huong-di-moi-cho-phu-nu-dap-ung-kem-voi-kich-thich-buong-trung-por\/","title":{"rendered":"PRP v\u00e0 h\u1ed7 tr\u1ee3 sinh s\u1ea3n \u2013 H\u01b0\u1edbng \u0111i m\u1edbi cho ph\u1ee5 n\u1eef \u0111\u00e1p \u1ee9ng k\u00e9m v\u1edbi k\u00edch th\u00edch bu\u1ed3ng tr\u1ee9ng (POR)"},"content":{"rendered":"\n
\"\"<\/a><\/figure>\n\n\n\n

Source: Orion<\/em><\/p>\n\n\n\n

Trong l\u0129nh v\u1ef1c h\u1ed7 tr\u1ee3 sinh s\u1ea3n, “\u0111\u00e1p \u1ee9ng k\u00e9m v\u1edbi k\u00edch th\u00edch bu\u1ed3ng tr\u1ee9ng” (Poor Ovarian Response \u2013 POR) l\u00e0 m\u1ed9t trong nh\u1eefng nguy\u00ean nh\u00e2n khi\u1ebfn nhi\u1ec1u ph\u1ee5 n\u1eef kh\u00f3 c\u00f3 thai d\u00f9 \u0111\u00e3 th\u1ef1c hi\u1ec7n th\u1ee5 tinh trong \u1ed1ng nghi\u1ec7m (IVF). \u0110\u00e2y l\u00e0 t\u00ecnh tr\u1ea1ng bu\u1ed3ng tr\u1ee9ng kh\u00f4ng t\u1ea1o \u0111\u1ee7 s\u1ed1 l\u01b0\u1ee3ng tr\u1ee9ng ho\u1eb7c ch\u1ea5t l\u01b0\u1ee3ng tr\u1ee9ng kh\u00f4ng \u0111\u1ea3m b\u1ea3o, d\u1eabn \u0111\u1ebfn t\u1ef7 l\u1ec7 \u0111\u1eadu thai th\u1ea5p. Vi\u1ec7c t\u00ecm ra gi\u1ea3i ph\u00e1p an to\u00e0n, hi\u1ec7u qu\u1ea3 cho nh\u00f3m b\u1ec7nh nh\u00e2n n\u00e0y lu\u00f4n l\u00e0 \u01b0u ti\u00ean l\u1edbn trong y h\u1ecdc sinh s\u1ea3n hi\u1ec7n \u0111\u1ea1i.<\/p>\n\n\n\n

M\u1ed9t h\u01b0\u1edbng \u0111i\u1ec1u tr\u1ecb ti\u1ec1m n\u0103ng \u0111ang \u0111\u01b0\u1ee3c quan t\u00e2m l\u00e0 ti\u00eam huy\u1ebft t\u01b0\u01a1ng gi\u00e0u ti\u1ec3u c\u1ea7u (PRP) t\u1ef1 th\u00e2n v\u00e0o bu\u1ed3ng tr\u1ee9ng<\/strong>. PRP l\u00e0 ch\u1ebf ph\u1ea9m sinh h\u1ecdc \u0111\u01b0\u1ee3c chi\u1ebft xu\u1ea5t t\u1eeb ch\u00ednh m\u00e1u ng\u01b0\u1eddi b\u1ec7nh, ch\u1ee9a nhi\u1ec1u y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng nh\u01b0 PDGF, TGF-\u03b2 v\u00e0 VEGF \u2013 c\u00f3 kh\u1ea3 n\u0103ng k\u00edch th\u00edch t\u0103ng sinh t\u1ebf b\u00e0o, t\u00e1i t\u1ea1o m\u00f4 v\u00e0 c\u1ea3i thi\u1ec7n tu\u1ea7n ho\u00e0n t\u1ea1i ch\u1ed7. Li\u1ec7u ph\u00e1p PRP \u0111\u00e3 \u0111\u01b0\u1ee3c \u1ee9ng d\u1ee5ng trong nhi\u1ec1u l\u0129nh v\u1ef1c y h\u1ecdc t\u00e1i t\u1ea1o, v\u00e0 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u m\u1edf r\u1ed9ng trong h\u1ed7 tr\u1ee3 sinh s\u1ea3n.<\/p>\n\n\n\n

M\u1ed9t nghi\u00ean c\u1ee9u m\u1edbi c\u00f4ng b\u1ed1 tr\u00ean Scientific Reports<\/em> (2025) \u0111\u00e3 kh\u1ea3o s\u00e1t hi\u1ec7u qu\u1ea3 c\u1ee7a ti\u00eam PRP v\u00e0o bu\u1ed3ng tr\u1ee9ng \u1edf 71 ph\u1ee5 n\u1eef b\u1ecb POR. Nh\u1eefng ng\u01b0\u1eddi tham gia \u0111\u1ec1u c\u00f3 ch\u1ec9 s\u1ed1 AMH th\u1ea5p (<1,2 ng\/mL), d\u01b0\u1edbi 5 nang no\u00e3n, v\u00e0 \u0111\u00e3 t\u1eebng th\u1ef1c hi\u1ec7n IVF tr\u01b0\u1edbc \u0111\u00f3 nh\u01b0ng ch\u01b0a th\u00e0nh c\u00f4ng. C\u00e1c b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c ti\u00eam PRP d\u01b0\u1edbi \u0111\u1ea7u d\u00f2 si\u00eau \u00e2m, chia l\u00e0m hai nh\u00f3m: m\u1ed9t nh\u00f3m ch\u1ec9 ti\u00eam 1 l\u1ea7n v\u00e0 nh\u00f3m c\u00f2n l\u1ea1i ti\u00eam 2 l\u1ea7n, c\u00e1ch nhau kho\u1ea3ng m\u1ed9t th\u00e1ng. Sau \u0111\u00f3, t\u1ea5t c\u1ea3 \u0111\u1ec1u ti\u1ebfn h\u00e0nh l\u1ea1i chu k\u1ef3 IVF \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 s\u1ef1 thay \u0111\u1ed5i.<\/p>\n\n\n\n

K\u1ebft qu\u1ea3 cho th\u1ea5y, c\u1ea3 hai nh\u00f3m \u0111\u1ec1u c\u00f3 s\u1ef1 c\u1ea3i thi\u1ec7n \u0111\u00e1ng k\u1ec3 v\u1ec1 d\u1ef1 tr\u1eef bu\u1ed3ng tr\u1ee9ng v\u00e0 \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u tr\u1ecb. Trung b\u00ecnh, n\u1ed3ng \u0111\u1ed9 AMH t\u0103ng t\u1eeb 0,33 l\u00ean 0,43 ng\/mL, s\u1ed1 l\u01b0\u1ee3ng nang no\u00e3n antral (AFC) t\u0103ng t\u1eeb 2,62 l\u00ean 3,80, v\u00e0 s\u1ed1 tr\u1ee9ng thu \u0111\u01b0\u1ee3c t\u0103ng t\u1eeb 2,32 l\u00ean 3,59 qu\u1ea3. \u0110\u1eb7c bi\u1ec7t, s\u1ed1 ph\u00f4i ch\u1ea5t l\u01b0\u1ee3ng cao c\u0169ng t\u0103ng r\u00f5 r\u1ec7t (t\u1eeb 0,73 l\u00ean 1,28 ph\u00f4i). \u0110\u00e2y l\u00e0 nh\u1eefng ch\u1ec9 s\u1ed1 quan tr\u1ecdng ph\u1ea3n \u00e1nh kh\u1ea3 n\u0103ng t\u1ea1o ph\u00f4i v\u00e0 ti\u1ec1m n\u0103ng mang thai sau IVF.<\/p>\n\n\n\n

M\u1ed9t \u0111i\u1ec3m \u0111\u00e1ng ch\u00fa \u00fd l\u00e0 k\u1ebft qu\u1ea3 gi\u1eefa nh\u00f3m ti\u00eam m\u1ed9t l\u1ea7n v\u00e0 nh\u00f3m ti\u00eam hai l\u1ea7n kh\u00f4ng c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t \u0111\u00e1ng k\u1ec3<\/strong>, ngo\u1ea1i tr\u1eeb vi\u1ec7c nh\u00f3m ti\u00eam hai l\u1ea7n c\u00f3 c\u1ea3i thi\u1ec7n r\u00f5 h\u01a1n \u1edf n\u1ed3ng \u0111\u1ed9 AMH. \u0110i\u1ec1u n\u00e0y g\u1ee3i \u00fd r\u1eb1ng m\u1ed9t l\u1ea7n ti\u00eam PRP \u0111\u00e3 \u0111\u1ee7 mang l\u1ea1i hi\u1ec7u qu\u1ea3 \u0111\u00e1ng k\u1ec3<\/strong> cho ph\u1ea7n l\u1edbn b\u1ec7nh nh\u00e2n, gi\u00fap \u0111\u01a1n gi\u1ea3n h\u00f3a quy tr\u00ecnh v\u00e0 ti\u1ebft ki\u1ec7m chi ph\u00ed m\u00e0 v\u1eabn \u0111\u1ea1t hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb.<\/p>\n\n\n\n

D\u00f9 c\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng c\u1ee7a PRP l\u00ean bu\u1ed3ng tr\u1ee9ng ch\u01b0a ho\u00e0n to\u00e0n \u0111\u01b0\u1ee3c hi\u1ec3u r\u00f5, nhi\u1ec1u gi\u1ea3 thuy\u1ebft cho r\u1eb1ng c\u00e1c y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng trong PRP gi\u00fap c\u1ea3i thi\u1ec7n m\u00f4i tr\u01b0\u1eddng bu\u1ed3ng tr\u1ee9ng, k\u00edch th\u00edch ph\u00e1t tri\u1ec3n nang tr\u1ee9ng v\u00e0 tr\u1ebb h\u00f3a m\u00f4 bu\u1ed3ng tr\u1ee9ng. M\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u th\u1eadm ch\u00ed c\u00f2n cho r\u1eb1ng PRP c\u00f3 th\u1ec3 k\u00edch ho\u1ea1t c\u00e1c nang tr\u1ee9ng \u201cng\u1ee7 y\u00ean\u201d, t\u1eeb \u0111\u00f3 l\u00e0m t\u0103ng s\u1ed1 l\u01b0\u1ee3ng tr\u1ee9ng c\u00f3 th\u1ec3 huy \u0111\u1ed9ng \u0111\u01b0\u1ee3c trong qu\u00e1 tr\u00ecnh IVF.<\/p>\n\n\n\n

Tuy nhi\u00ean, nghi\u00ean c\u1ee9u n\u00e0y v\u1eabn c\u00f2n m\u1ed9t s\u1ed1 gi\u1edbi h\u1ea1n, nh\u01b0 kh\u00f4ng \u0111\u00e1nh gi\u00e1 \u0111\u01b0\u1ee3c t\u1ef7 l\u1ec7 mang thai ho\u1eb7c kh\u1ea3 n\u0103ng s\u1ed1ng th\u1ef1c s\u1ef1 sau PRP, v\u00e0 c\u1ee1 m\u1eabu t\u01b0\u01a1ng \u0111\u1ed1i nh\u1ecf. Ngo\u00e0i ra, ch\u01b0a c\u00f3 nh\u00f3m \u0111\u1ed1i ch\u1ee9ng (control) \u0111\u1ec3 lo\u1ea1i tr\u1eeb kh\u1ea3 n\u0103ng PRP ch\u1ec9 l\u00e0 t\u00e1c \u0111\u1ed9ng t\u1ea1m th\u1eddi ho\u1eb7c do hi\u1ec7u \u1ee9ng c\u01a1 h\u1ecdc khi ti\u00eam v\u00e0o bu\u1ed3ng tr\u1ee9ng.<\/p>\n\n\n\n

D\u00f9 v\u1eady, \u0111\u00e2y v\u1eabn l\u00e0 m\u1ed9t nghi\u00ean c\u1ee9u c\u00f3 gi\u00e1 tr\u1ecb th\u1ef1c ti\u1ec5n cao. N\u00f3 m\u1edf ra c\u01a1 h\u1ed9i \u0111i\u1ec1u tr\u1ecb m\u1edbi cho nh\u00f3m b\u1ec7nh nh\u00e2n v\u1ed1n r\u1ea5t kh\u00f3 kh\u0103n trong IVF. N\u1ebfu b\u1ea1n ho\u1eb7c ng\u01b0\u1eddi th\u00e2n thu\u1ed9c nh\u00f3m ph\u1ee5 n\u1eef c\u00f3 d\u1ef1 tr\u1eef bu\u1ed3ng tr\u1ee9ng th\u1ea5p v\u00e0 t\u1eebng th\u1ea5t b\u1ea1i v\u1edbi IVF, h\u00e3y trao \u0111\u1ed5i v\u1edbi b\u00e1c s\u0129 chuy\u00ean ng\u00e0nh v\u1ec1 kh\u1ea3 n\u0103ng \u1ee9ng d\u1ee5ng PRP. D\u00f9 v\u1eabn \u0111ang trong giai \u0111o\u1ea1n nghi\u00ean c\u1ee9u, PRP h\u1ee9a h\u1eb9n l\u00e0 m\u1ed9t h\u01b0\u1edbng \u0111i \u0111\u01a1n gi\u1ea3n, \u00edt x\u00e2m l\u1ea5n, chi ph\u00ed h\u1ee3p l\u00fd v\u00e0 nhi\u1ec1u ti\u1ec1m n\u0103ng trong t\u01b0\u01a1ng lai.<\/p>\n\n\n\n

Source: https:\/\/www.nature.com\/articles\/s41598-025-02689-2<\/a><\/p>\n\n\n\n

\n\n\n\n

Biomedmart cung c\u1ea5p c\u00e1c b\u1ed9 kit thu nh\u1eadn PRP v\u00e0 PRF ch\u1ea5t l\u01b0\u1ee3ng cao, \u0111\u00e1p \u1ee9ng ti\u00eau chu\u1ea9n trong nghi\u00ean c\u1ee9u v\u00e0 \u1ee9ng d\u1ee5ng l\u00e2m s\u00e0ng.<\/strong> C\u00e1c b\u1ed9 kit \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf t\u1ed1i \u01b0u, gi\u00fap thu \u0111\u01b0\u1ee3c huy\u1ebft t\u01b0\u01a1ng gi\u00e0u ti\u1ec3u c\u1ea7u (PRP) v\u00e0 fibrin gi\u00e0u ti\u1ec3u c\u1ea7u (PRF) v\u1edbi hi\u1ec7u su\u1ea5t cao, n\u1ed3ng \u0111\u1ed9 ti\u1ec3u c\u1ea7u \u1ed5n \u0111\u1ecbnh v\u00e0 h\u00e0m l\u01b0\u1ee3ng y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng d\u1ed3i d\u00e0o nh\u01b0 PDGF, TGF-\u03b2, VEGF. S\u1ea3n ph\u1ea9m ph\u00f9 h\u1ee3p cho c\u00e1c chuy\u00ean gia y t\u1ebf v\u00e0 nh\u00e0 nghi\u00ean c\u1ee9u trong c\u00e1c l\u0129nh v\u1ef1c t\u00e1i t\u1ea1o m\u00f4, da li\u1ec5u, ch\u1ea5n th\u01b0\u01a1ng ch\u1ec9nh h\u00ecnh v\u00e0 nha khoa, \u0111\u1ed3ng th\u1eddi h\u1ed7 tr\u1ee3 ki\u1ec3m so\u00e1t ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 thao t\u00e1c chu\u1ea9n x\u00e1c trong to\u00e0n b\u1ed9 quy tr\u00ecnh x\u1eed l\u00fd m\u00e1u ngo\u1ea1i vi.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n","protected":false},"excerpt":{"rendered":"

Source: Orion Trong l\u0129nh v\u1ef1c h\u1ed7 tr\u1ee3 sinh s\u1ea3n, “\u0111\u00e1p \u1ee9ng k\u00e9m v\u1edbi k\u00edch th\u00edch bu\u1ed3ng tr\u1ee9ng” (Poor Ovarian Response \u2013 POR) l\u00e0 m\u1ed9t trong nh\u1eefng nguy\u00ean nh\u00e2n khi\u1ebfn nhi\u1ec1u ph\u1ee5 n\u1eef kh\u00f3 c\u00f3 thai d\u00f9 \u0111\u00e3 th\u1ef1c hi\u1ec7n th\u1ee5 tinh trong \u1ed1ng nghi\u1ec7m (IVF). \u0110\u00e2y l\u00e0 t\u00ecnh tr\u1ea1ng bu\u1ed3ng tr\u1ee9ng kh\u00f4ng t\u1ea1o \u0111\u1ee7 s\u1ed1 […]<\/p>\n","protected":false},"author":27,"featured_media":379,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[31],"tags":[],"class_list":["post-2055","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"jetpack_featured_media_url":"https:\/\/biomedmart.com.vn\/etc\/wp-content\/uploads\/2023\/05\/5PRP-kit-new-02.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/biomedmart.com.vn\/etc\/wp-json\/wp\/v2\/posts\/2055","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biomedmart.com.vn\/etc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biomedmart.com.vn\/etc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biomedmart.com.vn\/etc\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/biomedmart.com.vn\/etc\/wp-json\/wp\/v2\/comments?post=2055"}],"version-history":[{"count":5,"href":"https:\/\/biomedmart.com.vn\/etc\/wp-json\/wp\/v2\/posts\/2055\/revisions"}],"predecessor-version":[{"id":2066,"href":"https:\/\/biomedmart.com.vn\/etc\/wp-json\/wp\/v2\/posts\/2055\/revisions\/2066"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biomedmart.com.vn\/etc\/wp-json\/wp\/v2\/media\/379"}],"wp:attachment":[{"href":"https:\/\/biomedmart.com.vn\/etc\/wp-json\/wp\/v2\/media?parent=2055"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biomedmart.com.vn\/etc\/wp-json\/wp\/v2\/categories?post=2055"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biomedmart.com.vn\/etc\/wp-json\/wp\/v2\/tags?post=2055"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}